A team of researchers claims that they have discovered a treatment for hangovers, which means that, you will soon be able to say goodbye to this unpleasant symptom.
When it comes to the most excruciating, stomach-churning, and headache-inducing hangovers, sometimes a few of Berocca, some paracetamol, or eating oneself with a full English breakfast isn't quite enough to get rid of the symptoms.
In a stroke of good fortune, it appears that tactical chunders may soon be a thing of the past. According to reports, a group of Chinese scientists has discovered a probiotic that, while it may not cure your fear of beer, it could at least help you get out of bed and get some work done so that you don't waste an entire day.
The team of researchers developed an oral "hADH1B-expressing probiotic" to aid in the breakdown of alcohol in the digestive system in an effort to lessen the liver-damaging effects of alcohol.
Putting the emphasis on wine consumption - because who doesn't enjoy unwinding with a hearty bowl of pasta and a bottle of red at the end of the day - In order to test their probiotic, the scientists used some mice that had been given alcohol.
Before putting the probiotic to the test, the researchers monitored how long it took for the inebriated mice to recover on their own and found that it took anything between six and ten hours.
An hour after being subjected to the alcohol challenge, the mice were then put into what was called "an exercise recorder" and monitored every 15 seconds to determine how quickly they recovered from the effects of the alcohol, some with the assistance of the probiotic, and some without its assistance.
According to the findings of the research, the righting reflex was employed as the criterion to define drunkenness. In a nutshell, we positioned each mouse so that its abdomen and limbs were pointing upward while it was lying on its back on the ground. It was determined that the mouse had lost its usual righting reflex if it took more than 30 seconds for it to right itself after being flipped over.
The moment in time at which the righting response was lost was designated as the drunkenness point, and the length of time that elapsed between the first drink and intoxication was considered as the alcohol tolerance period.
According to the findings of the study, the mice that had been given the probiotic were able to regain their ability to exercise after around 5.5 hours. The process took approximately 6.4 hours for the mice that hadn't been given the probiotic.
In addition, one fourth of the mice who had taken the probiotic also did not lose their self-righting reflex and exercised throughout the whole process, whereas all of the mice" that hadn't taken it lost their locomotor ability following the alcohol challenge.
The probiotic not only decreased the amount of alcohol that was absorbed by the body, but it also increased the amount of time that the host was able to tolerate alcohol and decreased the amount of time it took for the host to recover after acute alcohol challenge.
Meng Dong, Ph.D., who participated in the research, stated that "We anticipate genetically altered probiotics can bring new ideas for the treatment of liver illnesses.
The improvement of recombinant probiotics in acute alcohol-induced liver and intestine damage has us quite thrilled, said the researchers. These findings are really promising.
The findings of the research were published in the journal Journal of Microbiology Spectrum with the title Oral Probiotic Expressing Human Ethanol Dehydrogenase Attenuates Damage Induced by Acute Alcohol Use in Mice.